Vasospastic disorders in the hand have been treated with surgical sympathectomy and recently with botulinum toxin A (BTX) injections in the palm. The purpose of this study was to evaluate if it is possible to obtain precise administration of BTX around the radial artery using a single ultrasound-guided injection. We present a novel technique using 1 single ultrasound-guided BTX injection around the radial artery to treat vasospastic symptoms. Ten patients were included in a pilot study. All patients were referred by a rheumatologist after been diagnosed with primary or secondary Raynaud. Under ultrasound guidance, BTX was injected around the radial artery and its comitant veins 3–5 cm proximal to the wrist. Ultrasound-guided injection of BTX allowed for a precise distribution of BTX into the perivascular space of the radial artery and its comitant veins. Intravascular injection could easily be excluded. One patient reported temporary reduced grip strength, most likely due to leakage of BTX to the flexor pollicis longus muscle. No other complications were registered. All patients reported reduced number of vasospastic episodes, warmer hands, and reduced pain. Ultrasound-guided injection enables precise administration of BTX in the space surrounding the radial artery and its comitant veins. This novel approach could be a promising treatment for vasospastic disorders of the hands in patients with primary and secondary Raynaud.
From the *Department of Clinical Medicine, Medical Imaging Research Group, UiT The Arctic University of Norway, Tromsø, Norway
†Department of Radiology, University Hospital of North Norway, Tromsø, Norway
‡Department of Plastic Surgery, University Hospital of North Norway, Tromsø, Norway.
Published online 12 July 2018.
Received for publication December 4, 2017; accepted April 20, 2018.
The publication charges for this article have been funded by a grant from the publication fund of UiT The Arctic University of Norway.
Disclosure: The authors have no financial interest to declare in relation to the content of this article. The publication charges for this article have been funded by a grant from the publication fund of UiT The Arctic University of Norway.
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Sven Weum, MD, PhD, Department of Clinical Medicine, Medical Imaging Research Group, UiT The Arctic University of Norway, 9037 Tromsø, Norway, E-mail: firstname.lastname@example.org
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