SHELDON H. PRESKORN, MD, is Professor and Chairman, Department of Psychiatry, University of Kansas School of Medicine-Wichita, and Chief Executive Officer and Medical Director, Clinical Research Institute, Wichita, Kansas. He has more than 25 years of drug development research experience at all levels (i.e., preclinical through Phase IV) and has been a principal investigator on over 200 clinical trials including every antidepressant marketed in the United States over the last 20 years. Dr. Preskorn maintains a website at 〈www.preskorn.com〉 where readers can access previous columns and other publications.