Clinical Case DiscussionThe Vision of Blindness—Sight Versus Insight: A Case Report and Literature Review of Self-enucleation (Oedipism)Vasilopoulou, Polyxeni MD, MC; Giannakopoulos, Orestis MD, MC, PhDc; Beis, Pavlos MD; Konstantinou, Gerasimos N. MDAuthor Information VASILOPOULOU, GIANNAKOPOULOS, BEIS: Department of Psychiatry, 251 Hellenic Airforce V.A. General Hospital, Athens, Greece KONSTANTINOU: Department of Psychiatry, 251 Hellenic Airforce V.A. General Hospital, Athens, Greece; and Department of Psychiatry, University of Toronto, Toronto, ON, Canada P.V. and G.N.K. contributed equally. The authors declare no conflicts of interest. Please send correspondence to: Gerasimos N. Konstantinou, MD, Clinical Psychiatrist, Centre of Addiction and Mental Health, 1025 Queen Street West, Toronto, ON, Canada M6J 1H4 (e-mail: [email protected]). Journal of Psychiatric Practice: July 2021 - Volume 27 - Issue 4 - p 333-337 doi: 10.1097/PRA.0000000000000558 Buy Metrics Abstract Self-enucleation or “Oedipism” is a rare ophthalmic and psychiatric emergency. Given the severity of its consequences, it requires proper medical management and that clinicians understand and be aware of the psychiatric presentation. Important clinical considerations include identification of various etiologies leading to self-enucleation, awareness of possible complications, and provision of appropriate care. We present a case of bilateral self-enucleation by a young male patient in the context of his first episode of psychosis and review the literature on this clinical entity. Ocular damage interferes significantly with activities of daily living and is associated with decreased quality of life so that identifying risk factors is of major importance to prevent this dangerous behavior. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.