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Successful Cerebral Aging: Clinical and Pharmacological Approaches to the Aging Brain


Journal of Psychiatric Practice®: January 2000 - Volume 6 - Issue 1 - p 33–38

The author first defines what he means by “successful cerebral aging.” He then discusses how major depression and dementia can interfere with this process and describes how what he terms “chronic stress dysphoria” can contribute to neuronal damage and mental impairment. The author then reviews a number of types of chronic stress, including health problems, loneliness, loss of autonomy, inactivity, and low self-esteem, and suggests possible solutions for minimizing their effect on successful aging.(Journal of Psychiatric Practice2000;6: 33-38)

LEHMANN: Former Professor Emeritus, Dept. of Psychiatry, McGill University, Montreal.

Please sent correspondence and reprint requests to: John M. Oldham, MD, New York State Psychiatric Institute, 1051 Riverside Dr., New York, NY 10032.

Presented in part at the Symposium on “Successful Cerebral Aging” on July 1, 1992, at the XVIII C.I.N.P. Congress in Nice. Also presented at Grand Rounds, St. Mary's Hospital, Montreal, on October 29, 1992 and at the Fifth Annual Research Conference on December 9, 1992, in Albany, NY.

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