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Evaluation of the Abaxis Piccolo Point-of-Care Chemistry Analyzer: Comparison to the Roche Cobas C501

Lee-Lewandrowski, Elizabeth PhD, MPH; Flood, James PhD; Zak, Richard BA, MBA; Griggs, David BS, MT-ASCP, MBA; Lewandrowski, Kent MD

Point of Care: The Journal of Near-Patient Testing & Technology: June 2017 - Volume 16 - Issue 2 - p 102–104
doi: 10.1097/POC.0000000000000136
Original Articles

In this study, we performed method validations for the Abaxis Piccolo Xpress assays for total protein, albumin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, total bilirubin, calcium, creatinine, urea nitrogen, and glucose compared with the Roche Cobas c501 analyzer. The validation included linear reportable range, imprecision, and assessment of accuracy and bias by method crossover. Although some biases between the methods were observed, these could be reconciled by adjustments to the normal reference ranges. Overall, we found that these assays performed at an accepted level for clinical use.

From the Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

Reprints: Kent Lewandrowski, MD, Pathology Laboratories and Molecular Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit St, Gray 5 Chemistry, Boston, MA 02114. E-mail:

The authors declare no conflict of interest.

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