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White Blood Cell Count in Primary Care: Comparison of Manual Microscopic Count to a Point-of-Care Instrument and a Central Laboratory Analyzer

Van Aelst, Sophie MSPharm; Verjans, Marie-Paul; Raes, Marc MD; Mewis, Alex MD

Point of Care: The Journal of Near-Patient Testing & Technology: June 2016 - Volume 15 - Issue 2 - p 59–60
doi: 10.1097/POC.0000000000000090
Original Articles

In primary care, our local pediatricians still perform white blood cell (WBC) count obtained by manual microscopy. The goal of this study was to compare microscopic WBC count and HemoCue WBC System point-of-care device in reliability and clinical use. We found a slope of 0.93 (95% confidence interval [CI], 0.79 to 1.14) and an intercept of 0.12 (95% CI, −2.21 to 1.61) for the comparison of ADVIA 2120i and HemoCue WBC system (n = 14), a slope of 1.09 (95% CI, 0.94 to 1.26) and an intercept of −1.08 (95% CI, −2.46 to 0.07) for the comparison of ADVIA 2120i and microscopic WBC count (n = 52), and a slope of 1.00 (95% CI, 0.89 to 1.14) and an intercept of −0.50 (95% CI, −1.51 to 0.34) for the comparison of microscopic WBC count and HemoCue system (n = 40). We can conclude that microscopic WBC count is still a reliable alternative for obtaining the WBC count in primary care practices.

From the *Department of Laboratory Medicine, Jessa Hospital; †Pediatric private practice; and ‡Department of Paediatrics, Jessa Hospital, Hasselt, Belgium.

Reprints: Sophie Van Aelst, MSPharm, Department of Laboratory Medicine, Jessa Hospital, Stadsomvaart 11, 3500 Hasselt, Belgium. E-mail:

The authors declare no conflict of interest.

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