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Protective Effect of Topical Antibiotics in Breast Augmentation

Pfeiffer, Philip K. M.D.; Kristiansen, Thomas B. M.D.; Hölmich, Lisbet R. M.D., D.M.Sc.

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Plastic and Reconstructive Surgery: January 2013 - Volume 131 - Issue 1 - p 115e
doi: 10.1097/PRS.0b013e318272a0cc
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We would like to thank Hua Li et al. for their comments regarding our article. We agree that antibiotics gradually become unstable over time and thus lose their effects. It is not our opinion that the protective effect of topical antibiotics is caused by active substrates 1 year after surgery.

During implantation, the breast implant is in close contact with the skin and therefore at risk of being contaminated.1 The beneficial effects of topical antibiotics are achieved at this early stage, where the antibiotics are active. Irrigating the implant pocket with a combination of saline and antibiotics may reduce the risk of a potential contamination. The use of topical antibiotics could therefore be considered as a supplement to the sterile technique, and we will continue to recommend its use.

Philip K. Pfeiffer, M.D.

Roskilde Private Hospital, Roskilde, Denmark

Thomas B. Kristiansen, M.D.

European Lifecare Group (Danske Lægers Vaccinations Service), Søborg, Denmark

Lisbet R. Hölmich, M.D., D.M.Sc.

Department of Plastic Surgery, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark


The authors have no financial interest to declare in relation to the content of this communication.


1. Moyer HR, Ghazi B, Saunders N, Losken A. Contamination in smooth gel breast implant placement: Testing a funnel versus digital insertion technique in a cadaver model. Aesthet Surg J. 2012;32:194–199.


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