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Sientra AlloX2 Short-Term Case Study, Surgical Pearls, and Roundtable Discussion

Zeidler, Kamakshi R. MD; Capizzi, Peter J. MD; Pittman, Troy A. MD

Plastic and Reconstructive Surgery: April 2018 - Volume 141 - Issue 4S - p 29S-39S
doi: 10.1097/PRS.0000000000004352
Original Articles

Background: The AlloX2 Breast Tissue Expander (Sientra, Santa Barbara, Calif.) is a unique device that contains a second port to allow for transdermal communication with the pocket around the implant. The injection dome of this expander contains two ports; one is used for traditional saline injection, and a new second port facilitates fluid drainage from the periprosthetic space through an integral drain. The AlloX2 allows for the treatment of seromas and diagnostic fluid sampling to identify bacteria and hone antibiotic treatment in the setting of periprosthetic infection. This device has a significant advantage over traditional expanders, given that seromas and infections are the most common complications in implant-based breast reconstruction, with or without the use of soft-tissue support matrix.

Methods: This article provides short-term case studies and surgical pearls from 3 surgeons who utilize the AlloX2 in primary breast reconstruction patients. Three surgeons implanted 40 primary reconstruction patients with AlloX2. Follow-up was approximately 6 months, per the standard of care. All patients implanted with AlloX2 underwent immediate reconstruction, with the exception of 1 delayed reconstruction.

Results: The most common complications the patients experienced were seromas. In most cases, the surgeons successfully used the second port to drain periprosthetic fluid.

Conclusions: The AlloX2 has been successful in treating seromas and should be considered a tool for noninvasive treatment of common complications of implant-based breast reconstruction. Three surgeons with varied backgrounds and techniques provide their surgical and postoperative management experiences and recommendations.

Campbell, CA; Charlotte, NC; and Washington, DC

From private practice and MedStar Georgetown University Hospital.

Received for publication August 28, 2017; accepted January 2, 2018.

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Disclosure:Drs. Zeidler, Capizzi, and Pittman are clinical study investigators for Sientra and receive standard research support for conducting their studies. The authors have no financial interest to declare in relation to the content of this article and received no financial support in the preparation of this article.

Kamakshi R. Zeidler, MD, 3803 South Bascom Avenue, Suite 100, Campbell, CA 95008,

Copyright © 2018 by the American Society of Plastic Surgeons