Breast implant–associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon neoplasia occurring in women with either cosmetic or reconstructive breast implants. The actual knowledge about BIA-ALCL deriving from the literature presents several limits, and it remains difficult to make inferences about BIA-ALCL epidemiology, cause, and pathogenesis. This is the reason why the authors decided to organize an evidence-based consensus conference during the Maurizio Bruno Nava (MBN 2016) Aesthetic Breast Meeting held in Milan in December of 2016. Twenty key opinion leaders in the field of plastic surgery from all over the world have been invited to express and discuss their opinion about some key questions on BIA-ALCL, trying to reach a consensus about BIA-ALCL cause, pathogenesis, diagnosis, and treatment in light of the actual best evidence.
Como, Milan, Naples, Catania, Salò, and Turin, Italy; Dallas and Houston, Texas; Boston, Mass.; Grand Rapids, Mich.; Alberta, British Columbia, Canada; Stockholm and Halmstad, Sweden; London, United Kingdom; Madrid, Spain; Buenos Aires, Argentina; and Bucharest, Romania
From Valduce Hospital; the University of Milan; the G.Re.T.A. Group for Reconstructive and Therapeutic Advancements; the Department of Clinical Medicine and Surgery, University of Naples “Federico II”; Villa Bella Clinic; the General Directorate of Medical Devices and Pharmaceutical Services, Italian Ministry of Health; National Cancer Institute “Regina Elena”; the Department of Clinical and Molecular Medicine, Sapienza University of Rome, Sant’Andrea Hospital; the Department of Plastic Surgery, Catholic University of Sacred Heart, University Hospital A. Gemelli; the Multidisciplinary Breast Unit, Azienda Ospedaliera Cannizzaro; University of Turin; the University of Texas Southwestern Medical Center; M. D. Anderson Cancer Center; Private practice; Partners in Plastic Surgery; Banff Plastic Surgery; Akademikliniken; Viktoriakliniken; London Royal Free Hospital; Plastic, Aesthetic and Reconstructive Surgery Department, Hospital Quiròn; Instituto Henry Moore, University of Buenos Aires; and S Clinic.
Received for publication April 6, 2017; accepted July 6, 2017.
Disclosure:None of the authors has a financial interest in any of the products, devices, or drugs mentioned in this article.
Nicola Rocco, M.D., University of Naples “Federico II”, Via Sergio Pansini 5, 80131 Naples, Italy, firstname.lastname@example.org