Secondary Logo

Journal Logo

Institutional members access full text with Ovid®

The Classification and Prognosis of Periocular Complications Related to Blindness following Cosmetic Filler Injection

Myung, Yujin M.D.; Yim, Sangjun M.D.; Jeong, Jae Hoon M.D., Ph.D.; Kim, Baek-Kyu M.D.; Heo, Chan-Yeong M.D., Ph.D.; Baek, Rong-Min M.D., Ph.D.; Pak, Chang-Sik M.D.

Plastic and Reconstructive Surgery: July 2017 - Volume 140 - Issue 1 - p 61-64
doi: 10.1097/PRS.0000000000003471
Cosmetic: Ideas and Innovations
Best Paper

Summary: Common side effects during hyaluronic acid filler injections are typically mild and reversible, but several reports of blindness have received attention. The present study focused on orbital symptoms combined with blindness, aiming to classify affected patients and predict their disease course and prognosis. From September of 2012 to August of 2015, nine patients with vision loss after filler injection were retrospectively reviewed. Ptosis, ophthalmoplegia, and enophthalmos were recorded over a 6-month follow-up, and patients were classified into four types according to periocular symptom manifestation. Two patients were categorized as type I (blindness without ptosis or ophthalmoplegia), two patients as type II (blindness and ptosis without ophthalmoplegia), two patients as type III (blindness and ophthalmoplegia without ptosis), and three patients as type IV (blindness with ptosis and ophthalmoplegia). The present study includes previously unpublished information about orbital symptom manifestations and prognosis combined with blindness caused by retinal artery occlusion after cosmetic filler injection.


Seongnam-si, Gyeonggi-do, Republic of Korea

From the Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seoul National University.

Received for publication August 3, 2016; accepted December 22, 2016.

Disclosure:The authors have no relevant financial or nonfinancial relationships in the products or services described, reviewed, evaluated or compared in this article.

Chang-Sik Pak, M.D., Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 300 Gumi-dong, Bundang-gu, Seongnam-si, Gyeonggi-do 463-707, Republic of Korea,

Copyright © 2017 by the American Society of Plastic Surgeons