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Reversal of Skin Aging with Topical Retinoids

Hubbard, Bradley A. M.D.; Unger, Jacob G. M.D.; Rohrich, Rod J. M.D.

Plastic and Reconstructive Surgery: April 2014 - Volume 133 - Issue 4 - p 481e–490e
doi: 10.1097/PRS.0000000000000043
Cosmetic: Special Topic
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Summary: Topical skin care and its place in plastic surgery today are often overlooked by clinicians formulating a plan for facial rejuvenation. Not only is it important to consider topical skin care as part of comprehensive care, but clinicians should also be educated with the data available in today's literature. This review aims to familiarize the reader with the biological processes of skin aging and evidence-based clinical outcomes afforded by various topical therapies. Furthermore, this review will focus on solar damage, the value of retinoids, and how they can be used in conjunction with forms of treatment such as chemical peel, dermabrasion, and lasers. Finally, guidelines will be provided to help the physician administer appropriate skin care based on the data presented.

Dallas, Texas

From the Department of Plastic Surgery, University of Texas Southwestern Medical Center.

Received for publication March 14, 2013; accepted August 13, 2013.

Disclosure: None of authors has any commercial associations or financial disclosures that might pose or create a conflict of interest with information presented in this article.

Rod J. Rohrich, M.D., University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9132,

©2014American Society of Plastic Surgeons