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A Multicenter, Prospective, Randomized, Single-Blind, Controlled Clinical Trial Comparing VASER-Assisted Lipoplasty and Suction-Assisted Lipoplasty

Nagy, Michael W. M.D.; Vanek, Paul F. Jr. M.D.

Plastic and Reconstructive Surgery: April 2012 - Volume 129 - Issue 4 - p 681e–689e
doi: 10.1097/PRS.0b013e3182442274
Cosmetic: Original Articles

Background: No scientific comparative study has demonstrated any statistically significant clinical improvement attributable to a new lipoplasty technology relative to traditional suction-assisted lipoplasty. This prospective study used a contralateral study design to evaluate postoperative differences between vibration amplification of sound energy at resonance (VASER)–assisted lipoplasty and suction-assisted lipoplasty.

Methods: Twenty female patients between the ages of 20 and 48 years received contralateral treatment with suction-assisted lipoplasty and VASER-assisted lipoplasty in one or more anatomical regions for a total of 33 regions. Patients received suction-assisted lipoplasty on one side of the body and VASER-assisted lipoplasty on the contralateral side. Patients were blinded to technology application. Aspirate was analyzed for blood content, and skin retraction was analyzed by measuring changes in ultraviolet light tattoos.

Results: Regarding skin retraction, the VASER-assisted lipoplasty–treated side resulted in a statistically significant improvement in skin retraction of 53 percent relative to suction-assisted lipoplasty (17 percent per liter versus 11 percent per liter, p = 0.003) with 33 paired sites using a two-tailed t test. Regarding blood loss, VASER-assisted lipoplasty treatment resulted in a statistically significant reduction in blood loss of 26 percent (11.2 versus 14.0 cc blood/100 cc) relative to the suction-assisted lipoplasty side (p = 0.019 with n = 20 using a two-tailed t test). Subjective measures (i.e., pain, swelling, appearance, and patient and physician preference) showed no statistical difference between the two methods at the 6-month evaluation.

Conclusions: The VASER-assisted lipoplasty method demonstrated improved skin retraction and reduction in blood loss compared with suction-assisted lipoplasty. This is the first study to demonstrate statistically significant and clinically relevant improvements in a new lipoplasty technology relative to suction-assisted lipoplasty.


Toms River, N.J.; and Mentor, Ohio

From the Personal Enhancement Center and private practice.

Received for publication February 13, 2011; accepted October 3, 2011.

Presented at Plastic Surgery 2009, the 78th Annual Meeting of the American Society of Plastic Surgeons, in Seattle, Washington, October 23 through 27, 2009.

This trial is registered under the name “VASER-Assisted Lipoplasty Compared With Suction-Assisted Lipoplasty (Contra-Lateral),” identification number NCT00731354 (

Disclosure:The authors do not have any stock ownership or equity interests with Sound Surgical Technologies. They do not hold any patent licensing arrangements and have not received any payment for conducting or publicizing the study described in this article.

Michael W. Nagy, M.D.; Plastic Surgery of the Face and Body, 1967 Highway 34, Suite 102, Wall, N.J. 07719,

©2012American Society of Plastic Surgeons