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Tissue Engineering in Plastic Surgery: A Review

Wong, Victor W. M.D.; Rustad, Kristine C. B.S.; Longaker, Michael T. M.D., M.B.A.; Gurtner, Geoffrey C. M.D.

Plastic and Reconstructive Surgery: September 2010 - Volume 126 - Issue 3 - p 858-868
doi: 10.1097/PRS.0b013e3181e3b3a3
Experimental: Scientific Review

Novel tissue- and organ-engineering strategies are needed to address the growing need for replacement biological parts. Collective progress in stem cell technology, biomaterials, engineering, and molecular medicine has advanced the state of regenerative medicine, yet many hurdles to clinical translation remain. Plastic surgeons are in an ideal position to capitalize on emerging technologies and will be at the forefront of transitioning basic science research into the clinical reconstructive arena. This review highlights fundamental principles of bioengineering, recent progress in tissue-specific engineering, and future directions for this exciting and rapidly evolving area of medicine.

Stanford, Calif.

From the Hagey Laboratory for Pediatric Regenerative Medicine, Stanford University.

Received for publication December 23, 2009; accepted February 24, 2010.

Disclosure: The authors have no financial interest in any of the products or devices mentioned in this article.

Geoffrey C. Gurtner, M.D., 257 Campus Drive, GK-201, Stanford, Calif. 94305,

©2010American Society of Plastic Surgeons