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Oncoplastic Breast Surgery for Cancer: Analysis of 540 Consecutive Cases [Outcomes Article]

Fitoussi, Alfred D. M.D.; Berry, M. G. M.S., F.R.C.S.(Plast.); Famà, Fausto M.D.; Falcou, Marie-Christine B.Sc.; Curnier, Alain F.R.C.S.(Plast.); Couturaud, Benoit M.D.; Reyal, Fabien M.D.; Salmon, Remy J. M.D., Ph.D.

Plastic and Reconstructive Surgery: February 2010 - Volume 125 - Issue 2 - p 454-462
doi: 10.1097/PRS.0b013e3181c82d3e
Breast: Original Articles

Background: Synchronous plastic and oncological surgery is undertaken to improve the security of excision margins and yield high-quality aesthetic outcomes when conventional breast-conserving therapy either anticipates poor results or is not possible.

Methods: A total of 540 consecutive patients underwent primary oncoplastic breast surgery for cancer with high tumor-to-breast volume ratios and locations precluding a good aesthetic result with simple tumor excision. A variety of techniques were employed at the Institut Curie between 1986 and 2007, and aesthetic outcomes were assessed on a five-point scale from 1 (excellent) to 5 (poor).

Results: The median age was 52 years (range, 28 to 90 years), and median follow-up was 49 months (6 to 262 months). Median tumor size was 29.1 mm (range, 4 to 100 mm), with most patients (72.3 percent) having a brassiere cup size of B or C. Close or involved margins occurred in 18.9 percent, with mastectomy being necessary in 9.4 percent. A satisfactory aesthetic outcome (ratings of 1 to 3) at 5 years was obtained in 90.3 percent. Five-year overall and distant disease-free survival rates were 92.9 and 87.9 percent, respectively, with local recurrence in 6.8 percent.

Conclusions: With local recurrence and survival rates similar to those for breast-conserving therapy, this series confirms the safety of oncoplastic breast surgery for tumors both high in volume and difficult in location. Highly satisfactory cosmetic outcomes extend the indications for conservative surgery, further reduce the mastectomy rate, and limit adverse aesthetic sequelae.

Paris, France

From the Departments of Surgery and Biostatistics, Institut Curie.

Received for publication April 9, 2009; accepted August 4, 2009.

Presented at the inaugural Oncoplastic and Reconstructive Breast Surgery meeting, in Nottingham, United Kingdom, June of 2008.

Disclosure: The authors have no financial interest to declare in relation to the content of this article.

M. G. Berry, M.S., F.R.C.S.(Plast.), Departement de Chirurgie, 25 rue d'Ulm, Institut Curie, Paris 75005, France,

©2010American Society of Plastic Surgeons