ANIANSSON G. MD; ALM, B. MD; ANDERSSON, B. MD, PHD; HAKANSSON, A.; LARSSON, P. MD, PHD; NYLÉN, O. MD, PHD; PETERSON, H. MD; RIGNÉR, P. MD; SVANBORG, M. MD; SABHARWAL, H. MD, PHD; SVANBORG, C. MD, PHDThe Pediatric Infectious Disease Journal: March 1994 ORIGINAL STUDIES: PDF Only Abstract This study analyzed the effect of breast-feeding on the frequency of acute otitis media. The protocol was designed to examine each child at 2, 6 and 10 months of age. At each visit nasopharyngeal cultures were obtained, the feeding pattern was recorded and the acute otitis media (AOM) episodes were documented. The analysis was based on 400 children from whom complete information was obtained. They represented 83% of the newborns in the study areas. By 1 year of age 85 (21%) children had experienced 111 AOM episodes; 63 (16%) had 1 and 22 (6%) had 2 or more episodes. The AOM frequency was significantly lower in the breast-fed than in the non-breast-fed children in each age group (P < 0.05). The first AOM episode occurred significantly earlier in children who were weaned before 6 months of age than in the remaining groups. The frequency of nasopharyngeal cultures positive for Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pnemoniae was significantly higher in children with AOM. At 4 to 7 and 8 to 12 months of age, the AOM frequency was significantly higher in children with day-care contact and siblings (P < 0.05 and < 0.01, respectively). The frequency of upper respiratory tract infections was increased in children with AOM but significantly reduced in the breast-fed group. © Williams & Wilkins 1994. All Rights Reserved.