Antimicrobial ReportsAcceptability of a Novel Levofloxacin Dispersible Tablet Formulation in Young Children Exposed to Multidrug-resistant TuberculosisPurchase, Susan E. MD*; Garcia-Prats, Anthony J. MD*; De Koker, Petra MSc*; Draper, Heather R. MSc*; Osman, Muhammad MD*; Seddon, James A. PhD*,†; Schaaf, H. Simon MD*; Hesseling, Anneke C. PhD*Author Information From the *Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Child Health, Stellenbosch University, Cape Town, South Africa †Centre for International Child Health, Imperial College London, London, United Kingdom. Accepted for publication December 1, 2018. Joint Global Health Trials Scheme of the Department for International Development, UK (DFID), Wellcome Trust; Medical Research Council (MRC, UK; Grant No MR/M007340/1), South African Medical Research Council (SA, MRC) Strategic Health Innovation Partnerships (SHIP; PI: A.C.H.); South African National Research Foundation SARChI Chair in Paediatric TB (A.C.H.). The authors have no conflicts of interest to disclose. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com). Address to correspondence: Susan Purchase, MD, Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Child Health, Stellenbosch University, Francie van Zijl Drive, Tygerberg, PO Box 241, Cape Town 8000. E-mail: firstname.lastname@example.org. The Pediatric Infectious Disease Journal: June 2019 - Volume 38 - Issue 6 - p 608-610 doi: 10.1097/INF.0000000000002268 Buy SDC Metrics Abstract Levofloxacin is used for the treatment and prevention of multidrug-resistant tuberculosis in children, but current adult formulations are poorly palatable. A questionnaire administered to caregivers of 27 children taking a novel 100 mg dispersible taste-masked levofloxacin tablet found the new formulation to be more palatable (69%) and easier to prepare (81%) than the adult formulation. This formulation may assist children to better adhere to anti-tuberculous therapy. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.