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Respiratory Viruses in Neonates: A Prospective, Community-based Birth Cohort Study

Sarna, Mohinder MAppEpi; Alsaleh, Asma PhD; Lambert, Stephen B. PhD; Ware, Robert S. PhD; Mhango, Lebogang P. BSc; Mackay, Ian M. PhD; Whiley, David M. PhD; Sloots, Theo P. PhD; Grimwood, Keith MD, FRACP

The Pediatric Infectious Disease Journal: December 2016 - Volume 35 - Issue 12 - p 1355–1357
doi: 10.1097/INF.0000000000001316
Brief Reports

A community-based birth cohort study collected weekly nasal swabs and recorded daily symptoms from 157 full-term infants. An average of 0.25 (95% confidence interval: 0.18, 0.34) respiratory virus infections per neonatal period were detected. Human rhinoviruses of diverse subtypes dominated; almost 50% were asymptomatic and continued rhinovirus detections may signify new genotypes. Respiratory viruses are common and often unrecognized in healthy neonates.

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From the *School of Public Health, Faculty of Medicine, UQ Child Health Research Centre, School of Medicine, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia; Department of Botany and Microbiology, King Saud University, Riyadh, Saudi Arabia; §Communicable Diseases Branch, Queensland Health, Brisbane, Queensland, Australia; Queensland Paediatric Infectious Diseases Laboratory, Centre for Children’s Health Research, Children’s Health Queensland, Brisbane, Queensland, Australia; ‖Public and Environmental Health-Virology, Forensic & Scientific Services, Department of Health, Coopers Plains, Queensland, Australia; **University of Queensland Centre for Clinical Research, Faculty of Medicine, The University of Queensland, Brisbane, Queensland Australia; ††School of Medicine, Menzies Health Institute, Queensland, Gold Coast campus, Griffith University; and ‡‡Departments of Paediatrics and Infectious Diseases, Gold Coast Health, Gold Coast, Queensland, Australia.

Accepted for publication May 9, 2016.

The authors have no conflicts of interest to disclose.

This study was supported by an Australian National Health and Medical Research Council (NHMRC) project grant (APP 615700) and a Children’s Hospital Foundation Queensland (CHFQ) program grant (CHFQ: 50006). M. S. is the recipient of an NHMRC Dora Lush Clinical Scholarship and a CHFQ PhD Clinical Scholarship. S. L. is the recipient of an NHMRC Early Career Fellowship and a CHFQ Mid-career Fellowship.

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Address for correspondence: Mohinder Sarna, MAppEpi, Centre for Children’s Health Research, 62 Graham Street, South Brisbane, Queensland 4101, Australia. E-mail:

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