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Relapse Among Infants Hospitalized for Bronchiolitis in Finland

Toivonen, Laura, MD, PhD; Hasegawa, Kohei, MD, MPH; Espinola, Janice, A., MPH; Camargo, Carlos, A., Jr., MD, DrPH; Jartti, Tuomas, MD, PhD

The Pediatric Infectious Disease Journal: January 8, 2018 - Volume Publish Ahead of Print - Issue - p
doi: 10.1097/INF.0000000000001888
Brief Reports: PDF Only

In a prospective cohort of children hospitalized for bronchiolitis, we examined the rate of and characteristics associated with bronchiolitis relapse. Bronchiolitis relapse was documented in 22 (6%) of 391 children and median time to relapse was 2 (interquartile range, 1-7) days. Relapse occurred more often in males. Prenatal smoking and smoke exposure in the home were also associated with relapse.

From the Department of Paediatrics and Adolescent Medicine, Turku University Hospital, University of Turku, Turku, Finland (LT, TJ); and Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA (KH, JAE, CAC).

Conflicts of Interest: The authors have no conflicts of interest.

Source of Funding: Dr. Laura Toivonen was supported by the Finnish Cultural Foundation, Helsinki, Finland. Dr. Tuomas Jartti was supported by the Academy of Finland (grant numbers 114034, 132595 and 267133) and the Finnish Medical Foundation, both in Helsinki, Finland.

Correspondence to: Laura Toivonen, MD, PhD, Department of Paediatrics and Adolescent Medicine, Turku University Hospital, 20521 Turku, Finland. E-mail:, Phone: +358-40-7020350

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