HIV ReportsChronic Lung Disease in Patients With Perinatally Acquired HIV in England: A Retrospective Case-Note ReviewEllis, Penelope K. BMedSci*; Shackley, Fiona MBChB†; Ugonna, Kelechi PhD*; Ryan, Clare E. MBChB‡; Hughes, David FRCR§; Owens, Stephen PhD¶; Brown, Philip MBChB‖; Riordan, Andrew FRCPCH**; Ilozue, Chinenye I. MBChB††; Rowland-Jones, Sarah L. PhD*; Collini, Paul J. PhD*Author Information From the *Department of Infection, Immunity and Cardiovascular Disease, University of Sheffield †Paediatric Immunology and Infectious Disease, Sheffield Children’s NHS Foundation Trust ‡Integrated Sexual health Service, Doncaster and Bassetlaw Teaching Hospitals NHS Trust §Department of Radiology, Sheffield Children’s Hospital ¶Department of Paediatric Immunology and Haematopoietic Stem Cell Transplantation, Great North Children’s Hospital, Newcastle upon Tyne Hospital National Health Service (NHS) Foundation Trust ‖Medical School, University of Newcastle **Department of Paediatric Infectious Diseases and Immunology, Alder Hey Children’s NHS Foundation Trust ††HIV Service, Liverpool University Hospitals NHS Foundation Trust, Liverpool, UK. Accepted for publication July 19, 2020. The authors have no conflicts of interest to disclose. P.K.E., P.J.C., F.S., and K.U. contributed to conception and design. P.K.E., C.E.R., S.O., P.B., A.R., and C.I.I. performed data collection. D.H. provided clinical advice on data interpretation. P.K.E. and P.J.C. performed data analysis. All authors contributed to writing the manuscript and approved the final version. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com). Address for correspondence: Paul J. Collini, Department of Infection, Immunity and Cardiovascular Disease, L Floor, University of Sheffield, Medical School, Beech Hill Road, Sheffield, S10 2RX, UK. E-mail: [email protected] The Pediatric Infectious Disease Journal: December 2020 - Volume 39 - Issue 12 - p 1103-1105 doi: 10.1097/INF.0000000000002874 Buy SDC Metrics Abstract Chronic lung disease (CLD) is common in individuals living with perinatally acquired HIV (PA-HIV) in southern/eastern Africa. Most of the UK PA-HIV population are African. We conducted a case-note review of CLD in 3 UK PA-HIV cohorts (n = 98). Bronchiectasis or obliterative bronchiolitis occurred in 8.1% of patients and ring/tramline opacities occurred in 19.2% of patients on chest radiograph. There may be unrecognized and underdiagnosed CLD among PA-HIV in the UK. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.