Immunology and Host ResponseFalse-positive Results of Quantiferon-Tb-Gold Assay in ChildrenQuintana-Ortega, Cristian MD*; Mendez-Echevarria, Ana MD, PhD*; del Rosal, Teresa MD, PhD*; Gonzalez-Muñoz, Miguel MD, PhD†; Baquero-Artigao, Fernando MD*Author Information From the *Pediatric Infectious and Tropical Diseases Department †Immunology Department, Hospital La Paz, Madrid, Spain. Accepted for publication January 16, 2020. The authors have no funding or conflicts of interest to disclose. Address for correspondence: Ana Méndez-Echevarría MD, PhD, Pediatric Infectious and Tropical Diseases Department, Hospital La Paz-IdiPAZ, Paseo de la Castellana 261, 28046, Madrid, Spain. E-mail: firstname.lastname@example.org. The Pediatric Infectious Disease Journal: July 2020 - Volume 39 - Issue 7 - p 620-623 doi: 10.1097/INF.0000000000002606 Buy Metrics Abstract We present a pediatric case series describing false-positive QuantiFERON-TB Gold In-tube (QFT-GIT) assay (QIAGEN, Germany) results observed in a tertiary hospital in Spain (2013–2018). During the study period, 7 of 737 test results were considered false-positives: 4 children with chronic medical conditions, 1 Mycobacterium lentiflavum lymphadenitis, 1 infant born to a mother with pulmonary tuberculosis, and 1 child exposed to a noninfectious tuberculosis patient. Data regarding interferon-gamma release assays false-positive results in children are scarce, and more studies are necessary to determine the rates of false-positive results in low-prevalence settings. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.