Immunology and Host ResponseProspective Evaluation of Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio for Intravenous Immunoglobulin Resistance in a Large Cohort of Kawasaki Disease PatientsLiu, Xiaoliang MD*,†,‡; Zhou, Kaiyu MD, PhD*,†,‡,§; Hua, Yimin MD, PhD*,†,‡,§; Wu, Mei MD*,¶; Liu, Lei MD*,¶; Shao, Shuran MD*,¶; Wang, Chuan MD, PhD*,†,‡,§Author Information From the *Department of Pediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China †Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education Chengdu, Sichuan, China ‡Key Laboratory of Development and Diseases of Women and Children of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China §The Cardiac development and early intervention unit, West China Institute of Women and Children’s Health, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China ¶West China Medical School of Sichuan University, Chengdu, Sichuan, China. Accepted for publication November 25, 2019. We thank the funding supporters [National Natural Science Foundation of China (No. 81800288, No. 81571515), Science-technology Support Plan Projects in Sichuan province (No. 2017SZ0117)]. None of authors declared any conflicts of interest. Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com). Address for correspondence: Chuan Wang, MD, PhD, Department of Pediatrics, West China Second University Hospital, Sichuan University, No. 20, 3rd section, South Renmin Road Chengdu, 610041, China. E-mail: firstname.lastname@example.org. The Pediatric Infectious Disease Journal: March 2020 - Volume 39 - Issue 3 - p 229-231 doi: 10.1097/INF.0000000000002566 Buy SDC Metrics Abstract The evaluation of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio for intravenous immunoglobulin resistance prediction was prospectively performed in a large cohort of Kawasaki disease patients. It was found that the predictive values of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio, alone or combined, were not good enough although they were identified as independent risk factors for intravenous immunoglobulin resistance. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.