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Vaccine Strain Varicella Infection in an Infant With Previously Undiagnosed Perinatal Human Immunodeficiency Type-1 Infection

Farnaes, Lauge, MD, PhD*; Coufal, Nicole G., MD, PhD; Spector, Stephen A., MD*

The Pediatric Infectious Disease Journal: April 2019 - Volume 38 - Issue 4 - p 413–415
doi: 10.1097/INF.0000000000002183
HIV Reports

A 15-month-old infant with a history of developmental delay and weight loss with multiple hospital admissions was diagnosed with a pustular lesion identified as vaccine strain varicella at the vaccination site. He was ultimately determined to be HIV infected following a protracted evaluation, which did not initially include HIV since his mother was confirmed HIV seronegative at 3 months gestation.

From the *Divisions of Pediatric Infectious Disease

Pediatric Critical Care, Department of Pediatrics, University of California San Diego, La Jolla, CA and Rady Children’s Hospital San Diego, La Jolla, CA.

Accepted for publication August 11, 2018.

The authors have no funding or conflicts of interest to disclose.

L.F. and N.C. collected and analyzed data and wrote the article, and S.A.S. diagnosed the patient, collected data, provided technical support and conceptual advice. All authors wrote, read and approved the final article.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (

Address for correspondence: Stephen A. Spector, MD, University of California San Diego, 9500 Gilman Dr. MC 0672, La Jolla, CA 92093-0672. E-mail:

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