There has been a substantial change in the prevalence and microbiologic characteristics of cases of acute otitis media secondary to the widespread use of pneumococcal conjugate vaccines. Current trends in nasopharyngeal colonization and the microbiology of acute otitis media support a change in the recommendation for antibiotic management of acute otitis media and acute bacterial sinusitis in children.
From the Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
Accepted for publication January 29, 2018.
Supported by Sinusitis in Children and the Nasopharyngeal Microbiome (R01 AI097172).
The authors have no conflicts of interest to disclose.
Address for correspondence: Ellen R. Wald, MD, Department of Pediatrics, UW School of Medicine & Public Health, Box 4108, 600 Highland Avenue, Madison, WI 53792. E-mail: firstname.lastname@example.org.