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Group A Streptococcal Brain Abscess in the Pediatric Population

Case Series and Review of the Literature

Capua, Tali, MD*; Klivitsky, Amir, MD; Bilavsky, Efraim, MD‡,§; Ashkenazi- Hoffnung, Liat, MD‡,§; Roth, Jonathan, MD; Constantini, Shlomi, MD, MSc; Grisaru-Soen, Galia, MD

The Pediatric Infectious Disease Journal: October 2018 - Volume 37 - Issue 10 - p 967–970
doi: 10.1097/INF.0000000000001947
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Background: Group A Streptococcus (GAS) is a rare cause of central nervous system infections.

Methods: We describe 3 new cases of GAS brain abscess in previously healthy children treated by us between 2015 and 2016 and review the 5 cases reported in the literature since 1988.

Results: All 8 children received early empiric antibiotic therapy and surgical intervention, and 5 made a full recovery.

Conclusions: GAS brain abscess is a rare infection; however its incidence may be rising. We suggest that if patients show symptoms such as fever, vomiting and lethargy, with contiguous infection such as otitis media, mastoiditis, sinusitis or meningitis, GAS brain abscess should be suspected. Prognosis is expected to be good with early implementation of appropriate treatment.

From the *Division of Pediatric Emergency Medicine, Department of Pediatrics

Pediatric Infectious Disease Unit, Dana-Dwek Children’s Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

Department of Pediatrics C, Schneider Children’s Medical Center, Petah Tiqva, Israel

§Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

Department of Pediatric Neurosurgery, Dana-Dwek Children’s Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Accepted for publication February 12, 2018.

The authors have no conflicts of interest to disclose.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com).

Address for correspondence: Galia Grisaru-Soen, MD, Pediatric Infectious Disease Unit, Dana-Dwek Children’s Hospital, Tel Aviv Sourasky Medical Center, 6 Weizman Street, Tel Aviv 6423906, Israel. E-mail: galiag@post.tau.ac.il.

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