Instructive CasesScabies, Periorbital Cellulitis and Recurrent Skin Abscesses due to Panton-Valentine Leukocidin-Positive Staphylococcus aureus Mimic Hyper IgE Syndrome in an InfantKrüger, Renate MD*; Hanitsch, Leif G. MD‡; Leistner, Rasmus MD§; Schneider-Burrus, Sylke MD¶; Hoppe, Pia-Alice MD*‡; Steinberg, Sylvia MD‖; Hauck, Fabian MD, PhD**††; von Bernuth, Horst MD, PhD*†‡‡§§Author Information From the *Department of Pediatric Pneumology and Immunology, ‡Department of Immunology, §Institute of Hygiene and Environmental Medicine, †Sozialpädiatrisches Zentrum, and ¶Department of Dermatology, Charité-Universitätsmedizin Berlin, Berlin, Germany; ‖Kinderarztpraxis Invalidenstr., Berlin, Germany; **Department of Pediatric Immunology and Rheumatology, ††Immunological Diagnostics Laboratory, Dr. von Hauner Childrens’s Hospital, Ludwig-Maximilians-Universität, Munich, Germany; ‡‡Labor Berlin GmbH, Fachbereich Immunologie, Charité-Universitätsmedizin -Vivantes, Berlin, Germany; and §§Berlin Center for Regenerative Therapies (BCRT), Charité-Universitätsmedizin Berlin, Berlin, Germany. Accepted for publication February 15, 2017. The authors have no funding or conflicts of interest to disclose. Address for correspondence: Renate Krüger, MD, Department of Pediatric Pneumology and Immunology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany. E-mail: [email protected]. The Pediatric Infectious Disease Journal: December 2017 - Volume 36 - Issue 12 - p e347-e348 doi: 10.1097/INF.0000000000001788 Buy Metrics Abstract We describe the clinical course of a 2-month-old infant who was evaluated for autosomal dominant Hyper IgE Syndrome based on eczema, periorbital cellulitis, skin abscesses, increased total IgE levels and blood eosinophilia. However, scabies and nasal colonization by Panton-Valentine Leucocidin-positive S. aureus were eventually diagnosed. After specific treatment, the child was asymptomatic. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.