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Endobronchial Lesions Caused by Nontuberculous Mycobacteria in Apparently Healthy Pediatric Patients

Kröner, Carolin MD; Griese, Matthias MD; Kappler, Matthias MD; Schoen, Carola MD; Hoffmann, Florian MD; Nicolai, Thomas MD; Reiter, Karl MD

The Pediatric Infectious Disease Journal: May 2015 - Volume 34 - Issue 5 - p 532–535
doi: 10.1097/INF.0000000000000606
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Pulmonary disease caused by nontuberculous mycobacteria in healthy children is rare, and its pathogenesis is unknown in most cases and standardized treatment is lacking. Here, we report various endobronchial manifestations in 5 patients including hitherto undescribed diffuse tracheobronchial granulomas in 2 patients. Bronchoscopic debulking was performed in all patients and tuberculostatic treatment in 4. All patients including 1 without tuberculostatic treatment showed remission.

Supplemental Digital Content is available in the text.

From the Department of Pediatrics, Dr. von Hauner Children’s Hospital, Ludwig-Maximilians-University, Munich, Germany.

Accepted for publication October 15, 2014.

The authors have no funding or conflicts of interest to disclose.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (www.pidj.com).

Address for correspondence: Karl Reiter, MD, Department of Pediatrics, Dr. von Hauner Children’s Hospital, Ludwig-Maximilians-Universitaet Muenchen, Lindwurmstr. 4a, 80337 Munich, Germany. E-mail: karl.reiter@med.uni-muenchen.de.

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