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Clostridium Septicum Brain Abscesses in a Premature Neonate

Sadarangani, Sapna P. MBBS*; Batdorf, Rachel MD; Buchhalter, Lillian C.; Mrelashvili, Anna MD§; Banerjee, Ritu MD, PhD; Henry, Nancy K. PhD, MD; Huskins, W. Charles MD, MS; Boyce, Thomas G. MD, MPH

The Pediatric Infectious Disease Journal: May 2014 - Volume 33 - Issue 5 - p 538–540
doi: 10.1097/INF.0000000000000203
Brief Reports

Brain abscesses in neonates are typically caused by Gram-negative organisms. There are no previously described cases caused by Clostridium septicum. We present a case of a premature male infant who developed recurrent episodes of suspected necrotizing enterocolitis followed by brain abscesses, cerebritis and ventriculitis caused by C. septicum.

From the *Division of Infectious Diseases; Department of Family Medicine, Mayo Clinic; Mayo Medical School; §Division of Child and Adolescent Neurology; and Division of Pediatric Infectious Diseases, Mayo Clinic, Rochester, MN.

Accepted for publication October 31, 2013.

The authors have no funding or conflicts of interest to disclose.

Address for correspondence: Sapna Sadarangani, MBBS, Division of Infectious Diseases, Mayo Clinic, 200 1st Street Southwest, Rochester, MN 55905. E-mail:;

© 2014 by Lippincott Williams & Wilkins, Inc.