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Unrecognized Pediatric Adult-type Tuberculosis Puts School Contacts At Risk

Steppacher, Anna MSc*†; Scheer, Ianina MD; Relly, Christa MD*†; Začek, Bea RN§; Turk, Alexander MD§; Altpeter, Ekkehardt MD; Berger, Christoph MD*†; Nadal, David MD*†

The Pediatric Infectious Disease Journal: March 2014 - Volume 33 - Issue 3 - p 325–328
doi: 10.1097/INF.0000000000000091
Brief Reports

Adolescents with an immigrant background who are from tuberculosis high-incidence regions were at highest risk to develop adult-type tuberculosis disease in a low-incidence region during a 20-year period. If diagnosis and treatment were delayed up to 6 months, latent tuberculosis infection was detected in almost half of the affected individuals’ school contacts.

Supplemental Digital Content is available in the text.

From the *Division of Infectious Diseases and Hospital Epidemiology, Children’s Research Center, and Division of Diagnostic Imaging, University Children’s Hospital of Zurich; §TB Zentrum bei Lunge Zürich, Lung League of the Canton of Zurich, Zurich; and Federal Office of Public Health, Division of Communicable Diseases, Berne, Switzerland.

Accepted for publication September 13, 2013.

The authors have no funding or conflicts of interest to disclose.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (

Address for correspondence: David Nadal, MD, Div. Infectious Diseases and Hospital Epidemiology, University Children’s Hospital, Steinwiesstrasse 75, CH-8032 Zürich, Switzerland. E-mail:

© 2014 by Lippincott Williams & Wilkins, Inc.