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Severe Pertussis in Newborns and Young Vulnerable Infants

Rocha, Gustavo MD*; Flôr-de-Lima, Filipa MD*; Soares, Paulo MD*†; Soares, Henrique MD*†; Pissarra, Susana MD*†; Proença, Elisa MD; Fernandes, Paula MD§; Quintas, Conceição MD; Martins, Teresa MD; Silva, Albina MD**; Guimarães, Hercília PhD*†

The Pediatric Infectious Disease Journal: October 2013 - Volume 32 - Issue 10 - p 1152–1154
doi: 10.1097/INF.0b013e31829f0b1a
Brief Reports

A retrospective chart review of 18 nonvaccinated newborns and infants admitted to 6 intensive care units in the north of Portugal between 2007 and 2012 revealed a high rate of admissions in 2012 along with significant rates of severe pulmonary hypertension and mortality. Hyperleukocytosis was significantly associated with a more severe clinical picture and mortality.

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From the *Division of Neonatology, Department of Pediatrics, Hospital de São João; Faculty of Medicine, Porto University; Division of Neonatology, Maternidade Júlio Dinis; §Neonatal and Pediatric Intensive Care Unit, Hospital Geral de Santo António; Division of Neonatology, Department of Pediatrics, Centro Hospitalar de Vila Nova de Gaia; Neonatal Intensive Care Unit, Department of Pediatrics, Hospital Pedro Hispano, Matosinhos, Porto; and **Neonatal Intensive Care Unit, Department of Pediatrics, Hospital de Braga, Braga, Portugal.

Accepted for publication May 30, 2013.

The authors have no funding or conflicts of interest to disclose.

Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (

Address for correspondence: Gustavo Rocha, MD, Serviço de Neonatologia, Departamento de Pediatria, Hospital de São João – Piso 2, Alameda Prof. Hernâni Monteiro, 4200 – 319 Porto, Portugal. E-mail:

© 2013 by Lippincott Williams & Wilkins, Inc.