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Fatal Outcome of Rhino-orbital-cerebral Mucormycosis Due to Bilateral Internal Carotid Occlusion in a Child After Hematopoietic Stem Cell Transplantation

Abela, Lucia MD*; Toelle, Sandra P. MD*; Hackenberg, Annette MD*; Scheer, Ianina MD; Güngör, Tayfun MD; Plecko, Barbara MD*

The Pediatric Infectious Disease Journal: October 2013 - Volume 32 - Issue 10 - p 1149–1150
doi: 10.1097/INF.0b013e31829e69e7
Brief Reports

Rhino-orbito-cerebral mucormycosis is a rare fulminant opportunistic fungal infection that particularly occurs in immunocompromised patients. We present a case of fatal invasive rhino-orbito-cerebral mucormycosis complicated by bilateral thrombotic occlusion of the internal carotid artery with consequent cerebral infarction in a 5-year-old boy after hematopoietic stem cell transplantation for acute pre–B-cell lymphoblastic leukemia

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From the Departments of *Neurology, Diagnostic Imaging and Immunology, University Children’s Hospital of Zurich, Zurich, Switzerland.

Accepted for publication May 29, 2013.

The authors have no funding or conflicts of interest to disclose.

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Address for correspondence: Barbara Plecko, MD, University Children’s Hospital, Steinwiesstrasse 75, CH-8032 Zurich, Switzerland. E-mail:

© 2013 by Lippincott Williams & Wilkins, Inc.