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Varicella Arthritis in Childhood: A Case Report and Review of the Literature

Bevilacqua, Sibylle MD*; Poircuitte, Jean-Manuel MD; Boyer, Laurence MD*; May, Thierry MD, PhD*; Lascombes, Pierre MD, PhD; Venard, Véronique PhD

The Pediatric Infectious Disease Journal: November 2011 - Volume 30 - Issue 11 - p 980-982
doi: 10.1097/INF.0b013e318223c0d8
Instructive Cases

Nonbacterial arthritis is a rare but well-recognized complication of acute varicella in children. Reported cases usually described monoarthritis of the knee that occurs at the onset of the rash or shortly after. Herein, we describe a case of arthritis of the hip that occurred in a 4-year-old girl 6 days before the onset of rash. The presence of varicella-zoster virus DNA in synovial fluid was confirmed by real-time polymerase chain reaction. A review of the literature reported 26 previous cases of aseptic arthritis due to varicella infection among children.

From the *Infectious and Tropical Diseases Unit, University Hospital of Nancy, Nancy, France; †Department of Pediatric Orthopedic Surgery, University Hospital of Nancy, Nancy, France; and ‡Laboratory of Virology, University Hospital of Nancy, Nancy, France.

Accepted for publication May 4, 2011.

The authors have no funding or conflicts of interest to disclose.

Address for correspondence: Sibylle Bevilacqua, Infectious and Tropical Diseases Unit, University Hospital of Nancy, Rue du Morvan, 54511 Vandoeuvre lès Nancy, France. E-mail:

© 2011 by Lippincott Williams & Wilkins, Inc.