We describe community-acquired rotavirus illness in 1359 children hospitalized at 12 centers in Canada between January 2005 and December 2007. The median age was 1.5 years. Almost half (48.6%) had significant dehydration, almost one-fifth (19%) had clinical sepsis and 7% had seizures at presentation. The median hospital stay was 3.4 days. Severe clinical presentations are less commonly described in surveillance programs.
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From the *Division of Infectious Diseases, CHEO Research Institute, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; †Vaccine Evaluation Center, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada; ‡Canadian Center for Vaccinology, IWK Health Center and Dalhousie University, Halifax, Nova Scotia, Canada; and §Stollery Children's Hospital and University of Alberta, Edmonton, Alberta, Canada.
Accepted for publication March 25, 2010.
Supported by a grant from GlaxoSmithKline Inc, Merck Canada and the Public Health Agency of Canada's Centre for Food-borne, Environmental and Zoonotic Infectious Diseases and Centre for Immunization and Respiratory Infectious Diseases.
Presented at the International Congress of Chemotherapy and Infection; June 18-21, 2009; Toronto, Ontario, Canada.
Address for correspondence: Nicole Le Saux, MD, FRCP(C), Division of Infectious Diseases, Children's Hospital of Eastern Ontario, 401 Smyth Rd, Ottawa, ON K1S 3C4, Canada. E-mail: firstname.lastname@example.org.
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