We examined nasal carriage of Staphylococcus aureus in otherwise healthy children presenting with skin and soft tissue infections. We found high rates of nasal colonization with S. aureus, but significant discordance between nasal and wound isolates. Recurrent skin and soft tissue infections were common but unrelated to baseline methicillin-resistant S. aureus nasal colonization status.
From the Departments of *Pediatrics, †Pathology, and ‡Hospital Epidemiology and Infection Control, Johns Hopkins Medical Institutions, Baltimore, MD.
Accepted for publication September 4, 2008.
Supported by Thrasher Research Foundation (Award NR-0001); The Johns Hopkins University School of Medicine General Clinical Research Center (grant M01-RR0052, from the National Center for Research Resources/NIH).
Address for correspondence: Aaron Chen, MD, Pediatric Emergency Medicine, CMSC 144-Pediatrics, 600 North Wolfe Street, Baltimore, MD 21287. E-mail: firstname.lastname@example.org.
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