The immunogenicity and safety of hepatitis A vaccine and pneumococcal conjugate vaccine, administered separately or concomitantly in children 15 months of age, were evaluated. After completed vaccinations, antihepatitis A and antipneumococcal geometric mean concentrations were similar across groups. Both vaccines were well-tolerated when given concomitantly during the second year of life.
From the *Department of Clinical Research, Development, and Medical Affairs, Vaccines for Viral Diseases, GlaxoSmithKline, King of Prussia, PA; †Henderson Pediatrics, Henderson, NV; ‡Boston University School of Boston, §Tufts University School of Medicine, Boston, MA; ¶Kentucky Pediatric and Adult Research, Bardstown, KY; and ∥Primary Physicians Research, Pittsburgh, PA.
Accepted for publication January 15, 2008.
This study was funded by GlaxoSmithKline Biologicals.
Address for correspondence: Andrew F. Trofa, MD, FACP, GlaxoSmithKline, Department of Clinical Research, Development, and Medical Affairs, 2301 Renaissance Boulevard, RN 0220, King of Prussia, PA 19406.