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Human Herpesvirus 8-Related Childhood Mononucleosis: A Series of Three Cases

Chen, Rong-Long MD*; Lin, Jung-Chung PhD; Wang, Pen-Jung MD*; Lee, Chan Ping PhD; Hsu, Yung-Hsiang MD§

The Pediatric Infectious Disease Journal: July 2004 - Volume 23 - Issue 7 - p 671-674
doi: 10.1097/01.inf.0000128776.45784.80
Instructive Cases

Human herpesvirus 8 has been implicated in the pathogenesis of a limited subset of lymphoproliferative disorders in adults, but its role in children is unclear. A prospective evaluation of children with atypical lymphocytosis residing in the Hualien area, where the incidence of adult Kaposi sarcoma is high, revealed 3 cases caused by human herpesvirus 8.

From the Departments of *Pediatrics, †Microbiology, ‡Biochemistry and §Pathology, College of Medicine, Tzu Chi University, Taiwan, Republic of China

Accepted for publication February 6, 2004.

Address for reprints: Rong-Long Chen, MD, Department of Pediatrics, College of Medicine, Tzu Chi University, 701, 3 Section, Chung Yan Road, Hualien, Taiwan 970. E-mail

© 2004 Lippincott Williams & Wilkins, Inc.