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TUNCER A. MURAT MD; GÜR, INCI MD; ERTEM, ULYA MD; ECE, AYDIN MD; TÜRKMEN, SAMI MD; DENIZ, BURHAN MD; GÜRMAN, ISIN MD; TUNCER, SAFIYE MD
The Pediatric Infectious Disease Journal: October 1988
ORIGINAL STUDIE: PDF Only
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Twenty children with meningococcal disease (15 with meningococcal meningitis and 5 with meningococcemia without meningitis) were treated with ceftriaxone, 80 to 100 mg/kg/day for 4 days. An additional 22 patients with meningococcal disease (13 with meningitis, 9 with meningococcemia without meningitis) were treated with penicillin G. On the basis of the Damrosch-Stiehm scoring system, 19 patients were classified in the poor prognostic group and were treated with antishock therapy. Clinical recovery time and normalization of CSF were compare in two groups. When the complications were compared, necrotic skin lesions were more frequently seen in the penicillin G group than in those who received ceftriaxone. Ceftriaxone is an effective and safe drug and offers the advantage of once daily administration for treatment of meningococcal disease in pediatric patients.

© Williams & Wilkins 1988. All Rights Reserved.