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Increased Levels of Proteoglycan Fragments and Stromelysin in Hip Joint Fluid in Legg-Calvé-Perthes Disease

Eckerwall, Göran; Lohmander, L.; Wingstrand, Hans

Journal of Pediatric Orthopaedics: March-April 1997 - Volume 17 - Issue 2 - p 266-269
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Summary: The concentrations of proteoglycan fragments and stromelysin were analyzed in joint aspirates in 19 children with Legg-Calvé-Perthes disease. We found increased levels of proteoglycan fragments and stromelysin consistent with the presence of synovitis, an important clinical and possibly also prognostic factor in these children.

From the Department of Orthopedics, University Hospital, Lund, Sweden.

Study conducted at the University Hospital, Lund, Sweden

Address correspondence and reprint requests to Dr. Göran Eckerwall, Department of Orthopedics, University Hospital of Lund, S-221 85 Lund, Sweden.

© Lippincott-Raven Publishers.