Illustrative CasesOut-of-Hospital Cardiac Arrest Due to Ventricular Fibrillation in a 5-Year-Old Pediatric PatientKlučka, Jozef MD∗; Juřenčák, Tomáš MD†; Štourač, Petr MD, PhD∗; Vít, Pavel MD, PhD†; Foralová, Vladimíra MD‡; Synková, Iva MSc§Author Information From the ∗Department of Paediatric Anaesthesiology and Intensive Care Medicine †Department of Paediatrics, University Hospital Brno, Faculty of Medicine, Masaryk University ‡Health Emergency Service for the South Moravian Region §Department of Medical Genetics, University Hospital Brno, Faculty of Medicine, Masaryk University, Brno, Czech Republic. The article was published with the nonfinancial support from Masaryk University and University Hospital Brno, Czech Republic. The article was published with the support by MZ ČR RVO (FNBr, 65269705) Czech Republic. Disclosure: The authors declare there are no conflict of interest. Reprints: Štourač Petr, PhD, Department of Paediatric Anaesthesiology and Intensive Care Medicine, University Hospital Brno, Jihlavská 20, 625 00 Brno, Czech Republic (e-mail: [email protected]). Pediatric Emergency Care: July 2020 - Volume 36 - Issue 7 - p e405-e407 doi: 10.1097/PEC.0000000000001444 Buy Metrics Abstract Out-of-hospital cardiac arrest in pediatric population is rare and predominantly has respiratory aetiology. Authors present the relatively unique case of out-of hospital cardiac arrest in 5-years old pediatric patient due to ventricular fibrillation (VF) as the initial rhythm during the advanced life support. The patient was resuscitated by his parents and the initial rhythm was VF. After defibrillation the patient was admitted to the pediatric intensive care were another two episodes of VF was detected and treated. After standard postresuscitation care, patient was weaned from sedation and extubated with good neurologic outcome. Genetic screening of the 7 genes associated with cardiac channelopathies (KCNQ1, KCNH2, SCN5A, KCNE1, KCNE2, RYR2, CASQ2) found mutation in gene KCHN2 and gene SCN5A, that were according to actual data considered benign. This case highlights the need for automated external defibrillator implementation in basic life support also in pediatric population and possible role of genetic predisposition in emergence of fibrillation. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.