The aims of the study were to determine the evolution of benign acute childhood myositis in children and to assess the relationship between creatine phosphokinase (CPK) values and myoglobinuria.
A retrospective study of patients with benign acute childhood myositis seen in 2 tertiary care university-affiliated pediatric hospitals during overlapping 4-year periods.
Demographic data, historical details, clinical, and laboratory results were extracted from the charts of children younger than 16 years with a CPK greater than 3 times normal. Complications, treatments, and outcomes were recorded.
Fifty-four children were included, 43 (80%) were male, and mean age was 7.3 years (median [range], 6 [3–16] years), none showed abnormal neurological findings, manifested hematuria, or developed renal failure. Mean CPK level at presentation was 1872 IU/L (range, 511–8086 IU/L). None developed renal failure, and there were no adverse outcomes on follow-up.
Acute childhood myositis is a predominantly benign disease. Neurological examination is usually normal and rhabdomyolysis is rare. Although severe pathological comorbid conditions must be excluded, a complete history and examination, coupled with simple blood and urine tests, can help minimize unnecessary diagnostic investigations.
From the *Division of Pediatric Emergency Medicine, Department of Pediatrics, Dana-Dwek Children Hospital, Sourasky Medical Center, University of Tel Aviv, Tel Aviv;
†Division of Pediatric Emergency Medicine, Shaare Zedek Medical Center, Jerusalem, Israel; and
‡Division of Pediatric Emergency Medicine, Clinical Pharmacology Toxicology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
Disclosure: The authors declare no conflict of interest.
Reprints: Miguel M. Glatstein, MD, Division of Pediatric Emergency Medicine, Dana-Dwek Children's Hospital, 6 Weizman St, Tel- Aviv 64239, Israel (e-mail: Nopasara73@hotmail.com).