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In-hospital Pediatric Cardiac Arrest in Honduras

Matamoros, Martha MD*; Rodriguez, Roger MD*; Callejas, Allison MD*; Carranza, Douglas MD*; Zeron, Hilda MD*; Sánchez, Carlos MD*; del Castillo, Jimena MD; López-Herce, Jesús MD, PhD for the Iberoamerican Pediatric Cardiac Arrest Study Network RIBEPCI

doi: 10.1097/PEC.0000000000000323
Original Articles
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Objectives The objective of this study was to analyze the characteristic and the prognostic factors of in-hospital pediatric cardiac arrest (CA) in a public hospital Honduras.

Methods A prospective observational study was performed on pediatric in-hospital CA as a part of a multicenter international study. One hundred forty-six children were studied. The primary end point was survival at hospital discharge. Univariate and multivariate logistic regression analyses were performed to assess the influence of each factor on mortality.

Results Cardiac arrest occurred in the emergency department in 66.9%. Respiratory diseases and sepsis were predominant causes of CA. Return of spontaneous circulation was achieved in 60% of patients, and 22.6% survived to hospital discharge. The factors related with mortality were nonrespiratory cause of CA (odds ratio [OR], 2.55; P = 0.045), adrenaline administration (OR, 4.96; P = 0.008), and a duration of cardiopulmonary resuscitation more than 10 minutes (OR, 3.40; P = 0.012).

Conclusions In-hospital CA in children in a developing country has low survival. Patients with nonrespiratory causes and those who need adrenaline administration and prolonged resuscitation had worse prognosis.

From the *Hospital Escuela, Tegucigalpa, Honduras; and †Pediatric Intensive Care Department, Instituto de Investigación del Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Disclosure: The authors declare no conflict of interest.

Reprints: Jesus Lopez-Herce, MD, PhD, Pediatric Intensive Care Department, Hospital General Universitario Gregorio Marañón, Dr Castelo 47 28009, Madrid, Spain (e-mail: pielvi@hotmail.com).

This study was supported in part by grant RT02377 from the Science and Technology for Development (CYTED) Program and by grant PI081167 from Carlos III Institute of Health, Spain.

© 2015 Lippincott Williams & Wilkins, Inc.