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Involuntary Movements Misdiagnosed as Seizure During Vitamin B12 Treatment

Carman, Kursat Bora MD*; Belgemen, Tugba MD; Yis, Uluc MD*

doi: 10.1097/PEC.0b013e3182aa475e
Illustrative Cases

Seizures and epilepsy are a common problem in childhood. Nonepileptic paroxysmal events are conditions that can mimic seizure and frequent in early childhood. Nonepileptic paroxysmal events can be due to physiological or exaggerated physiological responses, parasomnias, movement disorders, behavioral or psychiatric disturbances, or to hemodynamic, respiratory, or gastrointestinal dysfunction. Vitamin B12 deficiency is a treatable cause of failure to thrive and developmental regression, involuntary movements, and anemia. Involuntary movements rarely may appear a few days after the initiation of vitamin B12 treatments and might be misdiagnosed as seizure. Here, we report 2 patients who presented with involuntary movements with his video image.

From the Divisions of *Pediatric Neurology and †Pediatric Hematology, Gaziantep Children’s Hospital, Gaziantep, Turkey.

Disclosure: The authors declare no conflict of interest.

Reprints: Kursat Bora Carman, MD, Division of Pediatric Neurology, Gaziantep Children’s Hospital, Batıkent Mah. Vehbi Dinçerler Cad., Sena Apt. B Blok No:26/9, 27000, Şehitkamil- Gaziantep, Turkey (e-mail:

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