CME Review ArticlePediatric Scorpion Envenomation in the United States Morbidity, Mortality, and Therapeutic InnovationsSkolnik, Aaron B. MD*; Ewald, Michele Burns MD†Author Information Clinical Fellow (Skolnik), *Banner Good Samaritan Medical Toxicology Fellowship, Banner Good Samaritan Medical Center, Phoenix, AZ; Staff Physician and Fellowship Director (Burns Ewald), †Division of Emergency Medicine and Harvard Medical Toxicology Fellowship, Children’s Hospital Boston, Boston, MA. The authors and staff in a position to control the content of this CME activity and their spouses/life partners (if any) have disclosed that they have no financial relationships with, or financial interest in, any commercial organizations pertaining to this educational activity. Reprints Aaron B. Skolnik, MD, Banner Good Samaritan Medical Toxicology Fellowship, 925 E McDowell Rd, Second Floor, Phoenix, AZ 85006 (e-mail: [email protected]; [email protected]). Pediatric Emergency Care: January 2013 - Volume 29 - Issue 1 - p 98-103 doi: 10.1097/PEC.0b013e31827b5733 Buy Metrics Abstract In the Southwestern United States, the venom of the scorpion Centruroides sculpturatus (common name bark scorpion) can cause serious and potentially fatal neurotoxicity, with young children most vulnerable to its effects. Historically, advances in the quality of supportive care have made significant improvements in morbidity and mortality. In recent years, the development of effective antivenom therapies has changed the landscape of caring for these patients. This article reviews the background, pathophysiology, diagnosis, and treatment options for C. sculpturatus envenomation. Recent advances in immunotherapy and subsequent implications for pediatric emergency care providers are discussed. © 2013 Lippincott Williams & Wilkins, Inc.