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Pediatric Cannabinoid Hyperemesis: Two Cases

Miller, Joseph B. MD*; Walsh, Mark MD; Patel, Pankaj A. MD; Rogan, Michael MD; Arnold, Cliff BA; Maloney, Megan BS; Donnino, Michael MD§∥

doi: 10.1097/PEC.0b013e3181fe9189
Illustrative Cases

Cannabinoid hyperemesis has recently been described in the literature. It is a syndrome characterized by severe nausea and hyperemesis in the setting of chronic marijuana abuse and, to date, has been described only in adults. We describe the syndrome in 2 pediatric patients, for whom extensive gastrointestinal workups failed to identify a clear cause and cessation of marijuana use resulted in the alleviation of their symptoms. As in most published adult cases, compulsive bathing was present in both of these cases.

From the *Department of Emergency Medicine, Henry Ford Hospital, Detroit, MI; †Department of Emergency Medicine; ‡Department of Gastroenterology, Memorial Hospital, South Bend, IN; §Department of Emergency Medicine, and ∥Department Medicine/Division of Pulmonary Critical Care, Beth Israel Deaconess Medical Center, Boston, MA.

Reprints: Joseph Miller, MD, Department of Emergency Medicine, Henry Ford Hospital, CFP-2, 2799 W Grand Blvd, Detroit, MI 48202 (e-mail:

The authors report no conflicts of interests in this report.

© 2010 Lippincott Williams & Wilkins, Inc.