1Division of Critical Care, Department of Pediatrics, UCSF Benioff Children’s Hospital San Francisco, San Francisco, CA.
2Department Volunteer Services, UCSF Benioff Children’s Hospital Oakland, Oakland, CA.
3Department of Pediatric Critical Care, UMass Memorial Medical Center, Worcester, MA.
4Division of Critical Care Medicine, Department of Pediatrics, Mattel Children’s Hospital at UCLA Medical Center, Los Angeles, CA.
5Department of Family and Community Health, University of Pennsylvania, School of Nursing, Philadelphia, PA.
6Division of Pediatric Critical Care, Children’s Hospital of Richmond at VCU, Richmond, VA.
7Department of Medicine, UCSF Medical Center, San Francisco, CA.
8Department of Anesthesia, UCSF Medical Center, San Francisco, CA.
9Cardiovascular Research Institute, UCSF Medical Center, San Francisco, CA.
10Division of Pediatric Critical Care Medicine, C.S. Mott Children’s Hospital, Ann Arbor, MI.
*See also p. 1000.
Drs. Ward, Liu, Matthay, and Flori conceived of and designed the study. Drs. Ward, Curley, Valentine, Sapru, Willson, Flori, and Mr. Quinn participated in data acquisition and interpretation. Drs. Ward and Flori conducted the data analysis. All authors contributed to the interpretation of the analysis results. Dr. Ward prepared the first draft of the article, and all authors revised the draft critically. All authors have approved the final article for publication.
Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website (http://journals.lww.com/pccmjournal).
Supported, in part, by National Institutes of Health grants 5T32HD049303-08 (Dr. Ward), National Heart, Lung, and Blood Institute HL51856 (Dr. Matthay), and Charlotte Coleman Frey Fellowship Fund (Dr. Ward).
Dr. Ward received support for article research from the National Institutes of Health (NIH). His institution received funding from the Charlotte Coleman Frey Fellowship Fund and the NIH grants 5T32HD049303-08. Dr. Sapru received support for article research from the NIH. His institution received funding from the NIH. Dr. Curley received support for article research from the NIH. Her institution received funding from the National Institute of Nursing Research Prone positioning in pediatric acute lung injury RO1 NR05336-01. Dr. Liu received other support (Achaogen [Consultant], Chemocentryx [Consultant], Durect [Consultant], Z S Pharma [Advisory Board participant], and the American Society of Nephrology [Funding for travel]), received support for article research from the NIH, and received funding from Amgen (stockholder only, no other relationship). Her institution received funding from the NIH/National Heart, Lung and Blood Institute and the NIH/National Institute of Diabetes and Digestive and Kidney Disease. Dr. Matthay received support for article research from the NIH and received funding from RocheGenentec (Chair DSMB for asthma trials), GlaxoSmithKline (DSMB for critical care trial), Cerus Therapeutics (consultant for platelet trials), Quark Pharmaceuticals (consultant for lung injury trials), Biogen (consultant for lung injury studies in mice), and GlaxoSmithKline consultant for sepsis and ARDS trials). His institution received funding from GlaxoSmithKline (grant for studying biomarkers in sepsis patients) and Amgen (grant for studies of lung injury in mice). Dr. Flori received funding from biomarkers in sepsis patients San Joaquin Medical Center and received funding from the Law Offices of Vannucci. Her institution received funding from the NIH and Department of Defense. The remaining authors have disclosed that they do not have any potential conflicts of interest.
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