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Transposition of the Great Arteries and Common Variants

Wernovsky, Gil MD

Pediatric Critical Care Medicine: August 2016 - Volume 17 - Issue 8 - p S337-S343
doi: 10.1097/PCC.0000000000000819
Congenital Heart Disease
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Objectives: The objectives of this review are to discuss the physiology, perioperative management, surgical correction, and outcomes of infants with transposition of the great arteries and common variants undergoing the arterial switch operation.

Data Source: MEDLINE and PubMed.

Conclusion: The widespread adoption of the arterial switch operation for transposition of great arteries has been one of the more gratifying advances in pediatric cardiovascular care, and represents the simultaneous improvements in diagnostics, surgical and bypass techniques, anesthesia in the neonate, improvements in intensive care technology, nursing strategies, and system-wide care delivery. Many of the strategies adopted for the neonate with transposition of the great arteries have been translated to neonatal care for other congenital heart lesions. Continued work is necessary to investigate the effects of perioperative care on long-term neurodevelopmental outcomes, as well as collaboration between centers to spread “best practices” for outcome, cost, and morbidity reduction.

Department of Pediatrics, Section of Cardiology, Florida International University, Wertheim College of Medicine, Nicklaus Children’s Hospital, Miami, FL.

The author has disclosed that he does not have any potential conflicts of interest.

For information regarding this article, E-mail: gil.wernovsky@mch.com

Copyright © 2016 by the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies