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Sensorineural Hearing Loss and Language Development Following Neonatal Extracorporeal Membrane Oxygenation

van den Hondel, Desiree MD1; Madderom, Marlous J. MSc1; Goedegebure, Andre PhD2; Gischler, Saskia J. MD, PhD1; Mazer, Petra PhD1; Tibboel, Dick MD, PhD1; IJsselstijn, Hanneke MD, PhD1


In the article on page 62 of the January 2013 issue, some changes were inadvertently missed. They are the following:

On page 62, in the Objectives section of the abstract, line 4 should have been “speech- and language development”. Also, the corresponding author’s e-mail should have been listed as “”

On page 63, in the first column, lines 11-12 should have stated “speech- and language development and intelligence”.

On page 64, in the second column, line 23, the word “was” should have been removed.

Pediatric Critical Care Medicine. 14(2):237, February 2013.

Pediatric Critical Care Medicine: January 2013 - Volume 14 - Issue 1 - p 62–69
doi: 10.1097/PCC.0b013e31825b54ae
Neonatal Intensive Care

Objectives: To determine the prevalence of hearing loss in school-age children who have undergone neonatal extracorporeal membrane oxygenation treatment and to identify any effects of hearing loss on speech and language development.

Design: Prospective longitudinal follow-up study within the framework of a structured post-extracorporeal membrane oxygenation follow-up program.

Setting: Outpatient clinic of a level III university hospital.

Results: Tone audiometry was performed by standardized protocol in 136 children aged 5–12 yrs. Hearing loss was considered clinically significant when >20 dB. Hearing was normal in 75.7% of children. Five children (3.7%) had bilateral sensorineural or combined hearing loss; three of them received special audiological care (2.2% of total sample). Of the 24 children with congenital diaphragmatic hernia, 19 (79.2%) had normal hearing and only two (8.3%) had mild sensorineural hearing loss, unilateral in one of them. Follow-up at 24 months of age had shown normal verbal and nonverbal developmental scores. Language development and intelligence median (range) scores at 5 yrs of age were also normal: receptive language development 104 (55–133), syntactical development 104 (68–132), and lexical development 101 (50–141) for 89 children; intelligence quotient 104 (68–132) for 106 children. Scores did not differ among those with normal hearing, mild hearing loss, and moderate-to-severe hearing loss (p = 0.800, p = 0.639, p = 0.876, and p = 0.886, for the respective developmental tests).

Conclusions: We found normal language development and intelligence in a cohort of neonatal extracorporeal membrane oxygenation survivors. The prevalence of bilateral sensorineural hearing loss was in accordance with that of a larger series in the United States—which exceeds the prevalence in the normal population.

1 Intensive Care and Department of Pediatric Surgery, Erasmus MC – Sophia Children's Hospital, Rotterdam, The Netherlands.

2 Department of Audiology-ENT, Erasmus MC – Sophia Children’s Hospital, Rotterdam, The Netherlands.

Swart-van Essen Fund provided an unrestricted grant.

The authors have not disclosed any potential conflicts of interest.

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©2013The Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies