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INVASIVE UROTHELIAL CARCINOMA: DIAGNOSIS AND STAGING ON TURBT

McKenney, Jesse

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Pathology - Journal of the RCPA: 2010 - Volume 42 - Issue - p S13
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Invasive urothelial carcinoma is usually readily recognised, but the complex microanatomy of the urinary bladder often makes staging difficult in biopsy specimens. We will discuss recent studies describing heterogeneity in the musculature of the bladder and how this data may be applied to staging in difficult cases. Subtle morphologic variants of invasive urothelial carcinoma mimicking benign conditions (such as nested, tubular, and microcystic) will also be covered, as well as aggressive forms of urothelial carcinoma with potential therapeutic implications (micropapillary and small cell). Finally, we will discuss reporting of urothelial carcinomas in transurethral biopsy specimens with emphasis on what urologists need to know.

© 2010 Royal College of Pathologists of Australasia