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Recently described entities in the gynaecological tract

Reyes, M. Carolina; Cooper, Kumarasen

Pathology - Journal of the RCPA: August 2015 - Volume 47 - Issue 5 - p 414–422
doi: 10.1097/PAT.0000000000000277
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Summary: In recent years there have been significant advances in our understanding of female genital tract tumours due to the fact that new molecular abnormalities and translocations have been identified in certain neoplasms. Also, terminology of various lesions in the gynaecological tract has changed and a couple of new entities have been described.

In this review we will highlight some mesenchymal neoplasms including gynaecological perivascular epithelioid cell tumour (PEComa), inflammatory myofibroblastic tumour (IMT) occurring in the uterus and discuss and review terminology of endometrial stromal neoplasms.

A recently described entity, gastric type endocervical adenocarcinoma will be reviewed, summarising its most salient microscopic and clinical features. The newly proposed endocervical adenocarcinoma classification system by Silva and collegues will be reviewed as well.

Finally, a particular high-grade endometrial carcinoma (undifferentiated endometrial carcinoma) will be discussed highlighting the importance of its recognition and differential diagnosis.

Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, United States

Address for correspondence: M. Carolina Reyes, MD, Department of Pathology and Laboratory Medicine, University of Pennsylvania, 3400 Spruce Street, 6 Founders, Philadelphia, PA 19104, USA. E-mail: Carolina.Reyes@uphs.upenn.edu

Received 8 April, 2014

Revised 28 April, 2014

Accepted 6 May, 2014

© 2015 Royal College of Pathologists of Australasia
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