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Evaluation Of An Enzyme Immunoassay Kit For The Detection Of Clostridium Difficile Enterotoxin.

Bowman Rodney A.; Arrow, Suzan; Croese, Lynda; Riley, Thomas V.
Pathology - Journal of the RCPA: 1994
doi: 10.1080/00313029400169222
Original Article: PDF Only

: The Premier(TM) Clostridium difficile toxin A enzyme immunoassay (EIA) kit was evaluated for the detection of C. difficile enterotoxin in fecal samples. A total of 314 samples was tested by culture, cytotoxin detection and EIA kit. Compared to a combined culture/cytotoxin result the Premier(TM) EIA kit had a sensitivity of 88.3%, a sepcificity of 100%, a predictive value positive of 100% and a predictive value negative of 87.4%. Test results were available within 3 hrs providing a rapid and reliable means of detecting C. difficile enterotoxin.

(C) 1994 Royal College of Pathologists of Australasia

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