Case ReviewAncillary Testing of Salivary Gland Fine-Needle Aspiration Biopsy MaterialWong, Kristine S. MD∗; Krane, Jeffrey F. MD, PhD†Author Information From the ∗Brigham and Women's Hospital and Harvard Medical School, Boston, MA †David Geffen School of Medicine at UCLA, Los Angeles, CA. Reprints: Jeffrey F. Krane, MD, PhD, Department of Pathology, David Geffen School of Medicine at UCLA, 10833 LeConte Ave, Los Angeles, CA 90095. E-mail: [email protected]. The authors have no funding or conflicts to declare. AJSP: Reviews & Reports: 9/10 2020 - Volume 25 - Issue 5 - p 201-209 doi: 10.1097/PCR.0000000000000401 Buy Metrics Abstract Salivary gland tumors are often challenging to diagnose, particularly in cytologic material. Advances in our understanding of the molecular alterations in different salivary neoplasms have improved the ancillary testing tools available to resolve diagnostic uncertainty and refine clinical management options. Using a morphologically based approach focused on common basaloid and oncocytic/clear cell tumors, this review discusses the current role of immunohistochemical and fluorescence in situ hybridization–based testing as tools for diagnosing salivary gland tumors in fine-needle aspiration biopsy specimens. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.